Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

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How many grams of codeine are allowed per 100 ml in a Schedule III medication?

  1. 1.5 g

  2. 1.8 g

  3. 2.0 g

  4. 2.5 g

The correct answer is: 1.8 g

In the context of Schedule III medications, federal regulations specify that the maximum amount of codeine allowed in a combination product is 1.8 grams per 100 ml. This regulation is crucial because it helps to categorize and control the use of codeine based on its potential for abuse, while still allowing it to be available in lower doses for therapeutic use. Understanding the limits for controlled substances is vital for pharmacy practice, as it ensures compliance with both federal and state regulations governing the dispensing of medications. In this case, the choice of 1.8 grams aligns with the established guidelines, which define the permissible concentration of codeine in cough syrups and other combination products that are classified under Schedule III.