Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

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What is the maximum allowed amount of difenoxin in a Schedule V compound per dosage unit?

  1. 1 mg

  2. 0.5 mg

  3. 2 mg

  4. 3 mg

The correct answer is: 0.5 mg

The maximum allowed amount of difenoxin in a Schedule V compound per dosage unit is indeed 0.5 mg. Difenoxin is classified as a controlled substance in Schedule V primarily due to its potential for abuse when used in higher quantities, similar to other opioids, albeit to a lesser extent. The 0.5 mg limit serves as a regulatory measure aimed at minimizing misuse while still allowing for medicinal use. Schedule V drugs typically have a lower potential for abuse compared to drugs in higher schedules, and this specific limit reflects an attempt to balance access for therapeutic purposes with patient safety and public health considerations. The higher amounts in the other options do not align with the regulations governing Schedule V substances, which is why they are not valid choices in the context of this question. Understanding the thresholds set by regulatory bodies helps ensure that pharmacists dispense these medications within safe and legal limits.