Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

Which schedule of controlled substances is defined by a lower potential for abuse?

1. I

2. II

3. III

4. IV

The correct answer is: IV

The correct answer is associated with the classification of controlled substances based on their potential for abuse, medical use, and safety. Schedule IV substances are indeed defined by a lower potential for abuse compared to the higher schedules, particularly Schedule I and II. Controlled substances are categorized from Schedule I (highest potential for abuse and no accepted medical use) to Schedule V (low potential for abuse with accepted medical uses). Schedule IV substances, including drugs such as alprazolam and diazepam, have accepted medical uses and a potential for abuse that is considered lower than that of Schedules I, II, and III. This classification implies that while they can still lead to dependence or abuse, the risks associated with Schedule IV substances are deemed manageable when used appropriately under medical guidance. Thus, the underlying regulatory framework justifies why Schedule IV is recognized for its reduced potential for abuse.